An Overview of Mesothelioma Cancer

An Overview of Mesothelioma Cancer
An Overview of Mesothelioma Cancer - symptoms, Causes and treatment

An Overview of Mesothelioma Cancer – Mesothelioma is found in higher populations living near naturally occurring asbestos. Exposure to asbestos in the environment caused mesothelioma in places other than Turkey, including Corsica, Cyprus, Greece, China, and California.

What is Mesothelioma?

Mesothelioma is a very rare type and aggressive form of cancer that develops from the thin layer of cells lining the internal organs of the body. It is also known as the mesothelium.

This cancer most commonly affects the areas are lungs, chest wall.

Rather than, the rare area is the lining of the abdomen, the sac surrounding the heart or testis. Asbestos causes mesothelioma cancer. So, this malignant mesothelioma cancer is asbestos-related cancer.

Mesothelioma Definition:

It is a cancer of mesothelial cells, associates especially with exposure to asbestos.

An Overview of Mesothelioma Cancer

What is Mesothelioma disease:
A tumor formed on a thin layer of tissue that lines the lungs, stomach, heart and other internal organs. It was first recognized and described as a pathological entity by E. Wagner in the 1870s.

Mesothelioma symptoms:

These tumors begin as tiny nodules on the lining of the lungs or abdomen.
Mesothelioma doesn’t cause any symptoms until the tumors have grown in the body and spread all over.

So, it will be usually around cancer stages 3 and 4, in which tumors begin to press against the chest wall or abdominal cavity in the body.

It is impossible to recognize mesothelioma symptoms early in cancer’s development.
This disease doesn’t produce early symptoms to identify.

Mesothelioma Cancer | symptoms, Causes and treatment

Early signs of Mesothelioma

Here are the early signs of Mesothelioma

  • Dry cough or wheezing
  • Shortness of breath (dyspnea)
  • Respiratory complications
  • Pain in the chest or abdomen
  • Fever or night sweats
  • Pleural effusion (fluid around the lungs)
  • Fatigue
  • Muscle weakness

Mesothelioma Causes:

Asbestos is one of the primary mesothelioma causes. It comes in a variety of shapes and sizes types of asbestos that belong to the amphibole group are the most toxic.

The amphibole group includes much asbestos-like, tremolite, actinolite, crocidolite, amosite and anthophyllite asbestos.

The fibers that make up these amphibole varieties are thin, long and sharp. It is difficult to expel if they are once inhaled, and will fix in the chest area.

And they cause scarring and can eventually result in the development of cancerous tumors and mesothelioma disease.

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Mesothelioma Treatment:

Nevertheless of the reason why and how an individual develops mesothelioma disease.

Many doctors acknowledge that it is difficult cancer to treat. The disease has remained a long latency period for up to five decades.

Though the most standard treatments for cancer are not very effective in curing the disease, it can able to add only a few months to the patient’s life expectancy. This disease cannot be diagnosed until it reaches an advanced stage.

However, some newer treatments like photodynamic therapy and mesothelioma gene therapy have shown promise in fighting against this dreadful cancer.

Some tests are being developed that will help to treat the disease in the earlier stages, giving more hope for the mesothelioma patient.

This Cancer can classify by cell type, like epithelioid, sarcomatoid and biphasic. Both types of mesothelioma and cell can impact prognosis, diagnosis, and treatment options.

Most of the treatments in practice are chemotherapy, radiation, and surgery.

An Overview of Mesothelioma Cancer in most affected areas

That your history is exposure to asbestos, the cancer screenings help in mesothelioma diagnosis.

There is a better chance of qualifying your life if, you find the sign of this cancer in the initial stage.

Catching the sign in the early stage of mesothelioma can cure patients in receiving without aggressive treatment including chemotherapy, radiation therapy, and other surgeries.

In the early discovery of the disease, some aggressive therapies might be alternative.


Peritoneal Mesothelioma cancer

It is the most common type of cancer, diagnosed in about 10 to 20 percent of all mesothelioma cases.
Peritoneal cancer symptoms include:

  • Abdominal pain and inflation
  • Ascites or fluid in the stomach
  • Loss of weight


The Peritoneal treatment is only surgery to be conducted, which also with Hyperthermic Intra Peritoneal Chemotherapy (HIPEC).  With this treatment, 50 percent of patients can extend their lives for five years or more.


Pleural Mesothelioma cancer

This cancer forms in the lining of the lungs called the pleura. This cancer is the most common form of aggressive disease. Nearly 85 to 90 percent of cases mesothelioma is pleural.


  • Mild chest pain
  • Frequent coughing
  • Fatigue
  • Uneasy breath

The same symptoms are sometimes not accurate also associated with other health problems, such as lung cancer.

Surgery and chemotherapy can extend life expectancy.


Pericardial Mesothelioma

Pericardial cancer tumors form in the lining of the heart. Very few patients receive pericardial mesothelioma, there is only one percent of the total number of mesothelioma cases. It is not much danger.


  • Irregular heartbeat (Arrhythmia)
  • Mild chest pain
  • Fluid form in the heart

In the early stages of the patients may experience severe symptoms because of the tumors’ proximity.

Palliative and aim to reduce symptoms


Testicular Mesothelioma

Testicular cancer also diagnosed in less than one percent of all cases. This mesothelioma cancer forms in the lining of the testicles.


  • Testicular pain (severely)
  • The mass form on the testicle (white-yellow nodules)
  • Scrotum inflammation caused by fluid buildup


The treatment is surgery may be followed by chemotherapy with Cisplatin and pemetrexed or Alimta

Doctors also may offer therapy with radiation to kill any remaining cancer affected cells and prevent cancer from returning.

An Overview of Mesothelioma Cancer

Types of mesothelioma

Treatment options will be viable, depends on mesothelioma type and cell type. Mainly there are three types of mesothelioma cells

  • Epithelial cells
  • Sarcomatoid cells
  • Biphasic cells

Doctors in their treatment plan initially they consider cell type because the cells respond differently to a treatment. So, the doctors use cell type with mesothelioma type when determine the require treatment options and patient prognosis.

Epithelioid Mesothelioma

The above-said cell type typically responds well in treatment and has a more favorable prognosis than other cell types. Patients with this type of cancer have an average life expectancy is one year to two years.

Sarcomatoid Mesothelioma

The above-mentioned cells are known for aggressive growth, often patients not interested in a less favorable prognosis of six months.

Biphasic Mesothelioma

Both epithelial and sarcomatoid cells mixed in these biphasic mesothelioma tumors. In this condition, the prognosis varies depending on which cell type is dominant.

In biphasic mesothelioma patients with more epithelial cells will have a favorable response to treatment. But not in sarcomatoid cell treatment.

Categories of mesothelioma

Malignant mesothelioma

Malignant tumors grow or spread quickly, which can limit viable treatment options. In this malignant mesothelioma treatment patients live an average of one year to two years after diagnosis.

Benign mesothelioma

This above said mesothelioma is a non-cancerous form of the disease. Benign tumors can be treated by surgery with a low rate of recurrence and often be completely resected with surgery.


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